Saturday, August 20, 2011

Stem cells from mice

Stem cells from mice, The team of Japanese scientists have produced the sperm derived from stem cells of mice. Experiment could be a breakthrough for treating humans who experience infertility.

Stem cells from mice, Researchers at Kyoto University said that they managed to induce stem cells to create a pioneering sperm mice are transplanted into infertile male mice.

The mice then produced sperm that successfully used to fertilize eggs in a tube, known as IVF medical technology. Similarly, as quoted by the Straits Times, Sunday, 7 August 2011.

A paper published last week in the journal Cell academic said the resulting offspring through sperm will be healthy and fertile.

Mitinori Saitou, lead researcher also stated that their success can help develop a treatment of infertility in humans.

Meanwhile, outside experts are adding this group is the first step towards the treatment of infertility, although the use of the specifics are still far away.

Researchers in Japan using embryonic stem cells to develop a healthy mouse sperm that is expected in the future could help treat infertility in humans.

These findings, published in the journal Cell, marks a step forward to making use of stem cell regenerative medicine.

Stem cells are the main cells of the body and is the source of all the cells and fibers of the body. These cells can develop into various cell types and continued to proliferate.

Experts hope to use stem cells to treat various diseases and disorders such as cancer and diabetes.

scientists at Kyoto University, Japan move stem cells from mouse embryos and succeeded in turning it into early type of cells developed into the ovaries or sperm of rats.

These scientists then transplanting these cells into infertile mouse testis, which could then produce healthy sperm.

"Sperm is later removed from the testes and ovaries fertilized with (on a laboratory dish)," said senior researcher, Mitinori Saitou.

"After the insemination, we made two sets of embryos and then transferred to the uterus (womb) parent mice that gave birth to children of healthy mice with normal reproduction," says Saitou, who is an expert in anatomy and cell biology.

Used for human
Having successfully tested on mice, whether these findings could be useful to overcome the problem of human infertility?

Research has shown that scientists could use the cells that had been prepared to thrive in the sperm or ovaries.

"Now we have a lot of material to work. We can accelerate this research to the stage of studying the causes of human infertility," Saitou said.

Saitou-led team of scientists believe the same system can be done using human stem cells to generate healthy human sperm.

"We can use this knowledge to study human cells," he said.

He added that more research needs to be done because of the large differences between animal and human research.

Currently, Saitou said, the research team tried to produce ovaries mice using stem cells.


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